An eight-year analysis of 400,000 British adults found those with high levels of abdominal fat were twice as likely to develop uterine cancer. Visceral fat also increases the likelihood of the disease
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Women who have an apple shape are up to twice as likely to develop cancer, new research shows.
Scientists analyzed data from nearly 400,000 UK adults, including the amount of visceral fat around their waists.
Over an eight-year period, women in the high abdominal fat category were twice as likely to be diagnosed with uterine cancer.
The University of Glasgow results also show that visceral fat increases the risk of gallbladder cancer by 83%, kidney cancer by 39%, liver cancer by 25%, colon cancer by 14% and breast cancer by 11%.
The results will be presented at the European Congress on Obesity in Maastricht, the Netherlands.
The author Dr. Carlos Ceris told the Mirror: “We know that particular type of fat that you tend to get on your stomach is particularly bad. It’s the fat that accumulates around your internal organs. That means it has a rather stressful effect on them.
“This fat creates inflammatory markers, and this inflammation contributes to the development of cancer over the long term.
“More could be done by the NHS and health systems to show this increased risk [linked to visceral fat] for patients.”
Dangerous fat was measured using a new index developed by the researchers called the Visceral Obesity Index (VAI). They say it should be rolled out in the NHS to flag patients at risk.
Tam Fry, chair of the National Obesity Forum, said: “The message couldn’t be clearer. Fatty fat — the fat that makes your stomach bulge — can make you carcinogenic at every level.
“From an age when a child can get this right, the message should be drummed home. Cancer can kill you and far too many die from it far too young.”
Prof Tom Sanders of King’s College London said: ‘It has long been known that the risk of endometrial (uterine) cancer increases with obesity and that estrogen increases this risk. Body fat can increase tissue exposure to estrogen.”
The Visceral Obesity Index (VAI) includes weight circumference, body mass index (BMI), a test for triglycerides, and a test for high-density lipoprotein (HDL) cholesterol.
Triglycerides are a type of fat in your bloodstream. If you eat more calories than you need, the extra calories are converted into triglycerides. These triglycerides are stored in your fat cells for later use.
HDL or “good” cholesterol absorbs cholesterol and transports it back to the liver. The liver then flushes it out of the body.
High HDL cholesterol levels lower our risk of heart disease and stroke.
“These measurements, with the exception of waist circumference, are routinely performed in clinical practice,” added Dr. Added ceris.
“We need to investigate whether adding VAI to population-based screening tools could help us identify individuals at high risk of cancer at a much earlier stage.”
Karis Betts, Manager at Cancer Research UK, said: “Obesity causes 13 different types of cancer and is the second most preventable cause of cancer after smoking.
“More research is needed to uncover exactly how obesity causes cancer, including where we store fat in our bodies.
“One area of research is studying whether fat around organs, called visceral fat, poses a greater risk than fat under the skin.
“Although it’s not always easy, maintaining a healthy weight does reduce your risk of developing cancer, and you can increase the odds in your favor with healthy habits like a balanced diet and exercise.”
https://www.mirror.co.uk/lifestyle/health/apple-shaped-women-twice-likely-26875433 "Apple-shaped" women are twice as likely to suffer from some cancers, a study has found