‘Hunger Buster’ diabetes shot helps obese people lose 20% of their weight, study finds

Overweight volunteers who injected the highest dose of the “breakthrough” diabetes drug tirzepatide in a clinical trial lost 20% or more of their body weight

Tirzepatide helped people lose 20% of their body weight in a clinical study
Tirzepatide helped people lose 20% of their body weight in a clinical study

A “breakthrough” diabetes drug helped overweight volunteers lose 20% of their body weight in a clinical study.

For the study, 2,500 people in nine countries injected themselves with either tirzepatide or a placebo once a week for 72 weeks.

Of those given the highest dose of tirzepatide, 57% lost 20% or more of their body weight.

Only 3% of the placebo patients lost that much.

First author Dr. Ania Jastreboff from Yale University in the US said: “We should treat obesity like any other chronic disease – with effective, safe approaches that target the underlying disease mechanisms. Tirzepatide can do just that.”

Tirzepatide combines mimics of two hormones, GLP-1 and GIP, that our gut naturally releases after eating to make us feel satisfied.







The diabetes drug has been described as a “game changer”.
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Picture:

(Getty Images/Blend Images)

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Another anti-obesity drug, Semaglutide, which contains only a GLP-1 mimetic, was considered a breakthrough in weight loss when it was approved for use in February.

But patients taking it only lost an average of 15% of their weight, 5% less than those taking tirzepatide.

The latest evidence suggests that the GIP in tirzepatide makes it more effective.

dr Simon Cork of Anglia Ruskin University said: “These drugs are game-changing.” Prof Sir Stephen O’Rahilly of Cambridge University said: “The results of this study are very impressive.”

He added that the patients also showed improved cardiovascular and metabolic health.

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https://www.mirror.co.uk/news/uk-news/hunger-buster-diabetes-jab-helps-27161814 'Hunger Buster' diabetes shot helps obese people lose 20% of their weight, study finds

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