Millions of Brits treat general pain with ibuprofen, but it can cause serious organ damage when mixed with other drugs, new research suggests
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One of the most common over-the-counter pain relief options in the UK, Ibuprofen is used to treat common ailments from headaches to menstrual cramps and toothaches.
Brits take millions of these pills every year with no major side effects, but scientists are now warning they shouldn’t be mixed with common blood pressure medicines after a study found they could damage your kidneys.
People living with high blood pressure are often prescribed diuretic water loss pills and renin-angiotensin system (RSA) inhibitors, but combining them with ibuprofen could be a “triple punch” for acute kidney damage.
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Researchers at the University of Waterloo used a computer-simulated drug study to model the interaction of ibuprofen with these common high blood pressure treatments and determine their effects on the kidneys.
The “triple punch” of combining water loss pills with an RSA inhibitor like Advil plus ibuprofen reduces your kidney’s ability to process these drugs and can cause major damage.
The study’s scientists advise people being treated for high blood pressure to talk to their doctor about choosing a different pain reliever.
The NHS already advises against taking ibuprofen in the later stages of pregnancy and for anyone experiencing shortness of breath after taking aspirin or ibuprofen.
Many people are unaware of these potential side effects from taking the pain reliever. More broadly, ibuprofen should also not be taken by people with asthma, Crohn’s disease, stomach ulcers, arterial disease, heart disease, or a history of stroke.
‘It’s not like anyone who happens to be taking this combination of drugs is going to have problems,’ said Professor Anita Layton, one of the study’s authors.
“But research shows it’s a problem enough that you should exercise caution.”
“Diuretics are a family of drugs that cause the body to hold less water,” Layton said. “Dehydration is a major factor in acute kidney damage, and that’s when the RAS inhibitor and ibuprofen hit the kidney with that triple whammy.
“If you’re on these high blood pressure medications and need a pain reliever, consider acetaminophen instead.”
https://www.mirror.co.uk/lifestyle/health/ibuprofen-warning-mixing-painkiller-blood-26910884 Ibuprofen warning: Mixing pain relievers and blood pressure medications can damage the kidneys