Police are seeking witnesses to the accident on the A270 Old Shoreham Road in Hove, which happened just before 5pm on Tuesday.
Police said a motorbike collided with a white BMW car and a pedestrian at the junction with St Josephs Close.
The motorcyclist and pedestrian were taken to hospital with serious injuries.
Anyone who has seen what happened, or the circumstances leading to the crash, or has relevant CCTV or dashcam footage is asked to contact police online or via 101 quoting Operation Bookham .
https://www.theargus.co.uk/news/20291194.pedestrian-motorcyclist-seriously-injured-crash-a270/?ref=rss Pedestrians and motorcyclists seriously injured in crash on A270